search
The following results are related to Neuroinformatics. Are you interested to view more results? Visit OpenAIRE - Explore.

  • Neuroinformatics
  • Open Access
  • Spanish; Castilian

Relevance
arrow_drop_down
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Noriega Puente, Andrea;

    RESUMEN: El glioma es el tipo de tumor cerebral más común, presentando distintos grados de malignidad y agresividad, así como un pronóstico variable. La gran variabilidad que caracteriza a estas lesiones implica un estudio completamente único, así como un tratamiento personalizado. Es por esto que la segmentación manual de este tipo de lesiones supone tanto un gran consumo de tiempo como un trabajo duro para el experto, el cual implica el análisis multimodal de varias secuencias diferentes, normalmente, de Resonancia Magnética. En este trabajo se presenta un modelo de segmentación automática de gliomas de alto grado, HGG, cuya arquitectura se basa en el empleo de redes neuronales convolucionales simétricas, denominada U-Net. Para el entrenamiento del modelo se ha hecho uso del conjunto de datos del Data Challenge BraTS 2018 (Brain Tumor Segmentation), compuesto por un total de 237 estudios de IRM, 162 HGG y 75 LGG, de los que solo se han empleado los primeros. Los resultados en cuanto a la obtención de mapas binarios de segmentación de los tumores han sido positivos. Se ha calculado el coeficiente DICE medio, relacionado con la calidad de la determinación de la forma del tumor, logrando 0:64 +- 0:39 para el modelo entrenado con imágenes T1, y 0:57 +- 0:41 para el modelo entrenado con secuencias T1 con contraste. Cualitativamente se ha observado además un buen desempeño a la hora de localizar espacialmente los tumores, incluso si la forma no es determinada tan precisamente. ABSTRACT: Glioma is the most common type of brain tumor, having di_erent degrees of malignancy and aggressiveness, as well as a variable prognosis. The great variability of these pathologies implies a completely unique study, as well as a personalized treatment. This is why the manual segmentation of brain tumors by an expert entails both a big time consumption and a really hard work, involving the multimodal analysis of several different sequences of Magnetic Resonance. In this project, an automatic segmentation model of high-grade glioma, HGG, is introduced, whose architecture is based in symmetric convolutional neural networks, called U-Net. For training the model, data from the Data Challenge BraTS 2018 (Brain Tumor Segmentation) have been used, consisting of a total of 237 MRI studies, 162 HGG cases and 75 LGG cases, from which only the first ones have been used. Resulting binary segmentation map of the tumors have been positive. The mean DICE coe_cient, related to the quality of tumor shape determination, has been calculated, achieving 0:64 +- 0:39 for the model trained with T1 sequences, and 0:57 +- 0:41 for the model trained with T1 enhanced sequences. Qualitatively, good performance has also been observed when determining spatial location of the tumors, even if the shape is not determined so precisely. Máster en Ciencia de Datos

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ UCreaarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    UCrea
    Master thesis . 2019
    License: CC BY NC ND
    Data sources: UCrea
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ UCreaarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      UCrea
      Master thesis . 2019
      License: CC BY NC ND
      Data sources: UCrea
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mongiat, Lucas A.;

    A la fecha, se conocen 24 variantes de la Hormona Liberadora de Gonadotrofinas (GnRH). Se ha demostrado en numerosos vertebrados,incluyendo mamíferos, que más de una variante de GnRH son expresadas en una misma especie. En la rata existen evidencias postulando la presencia de diferentes variantes de GnRH, conjuntamente con la ya caracterizada GnRH-I, ellas son: GnRH-II, gpGnRH, sGnRH y lGnRH-III. Por otro lado, se demostró la presencia de más de un receptor de GnRH (GnRHR) en distintas especies. Sin embargo, en un modelo ampliamente utilizado como lo es la rata, hay controversia acerca de los sistemas de GnRH presentes. El objetivo de esta Tesis, consiste en estudiar los distintos sistemas de GnRH presentes en rata. En este trabajo estudiamos extractos peptídicos de distintos tejidos mediante diferentes sistemas de RP-HPLC conjugado con detección con distintos RIA para GnRH, determinamos la actividad biológica de las diferentes variantes postuladas en rata y abordamos la búsqueda de un receptor diferente del conocido GnRHR tipo-I. Concluimos que, la actividad gonadotrófica hipofisaria parece estar mediada por el sistema GnRH-I/GnRHR tipo I. Demostramos la presencia de HypGnRH, aportamos fuertes evidencias de la expresión de GnRH-II en cerebro e hipófisis y postulamos la presencia de gpGnRH. No encontramos evidencias de la expresión de lGnRH-III o sGnRH. Establecimos que GnRH-I y GnRH-II poseen similares potencias en cuanto a su actividad hipofisaria, mientras que sGnRH y gpGnRH poseen una menor potencia. No detectamos efectos fisiológicos de lGnRH-III en células hipofisarias. Proponemos la existencia en células ováricas de un sitio de unión a GnRH diferente del expresado en hipófisis. Este trabajo evidencia la existencia de distintos sistemas de GnRH presentes en rata. Estos sistemas podrían participar en diferentes funciones como ser la modulación de la conducta sexual (ej GnRH-II), la regulación autócrina/parácrina de la respuesta gonadotrófica hipofisaria, regulación intra-ovárica de la función gonadal. To date, 24 Gonadotropin Releasing Hormone (GnRH) variants have been described. In several vertebrates, including mammals, more than one GnRH variant are co-expressed in a single species. In the rat, there are evidences postulating various GnRH variants, together with GnRH-I, they are: GnRH-II, gpGnRH, sGnRH and lGnRH-III. On the other hand, different receptors for this hormone have been demonstrated in several species. However, in such an important model as the rat, there is controversy regarding the GnRH systems present. The aim of this Thesis was to study the different GnRH systems in the rat. Here, we characterize peptidic extracts from rat tissues by different RP-HPLC systems together with GnRH RIA detection; we study the biologic activity of the GnRH variants postulated to be present in rat and examine the possible existence of a receptor distinct from the already known type-I GnRHR. We conclude that gonadotropic activity in the rat is mediated by the GnRH-I/type-I GnRHR system. In addition, we demonstrate the expression of hypGnRH, provide strong evidences for GnRH-II presence in brain and pituitary and show experimental data supporting gpGnRH existence in the rat. However, we do not detect either lGnRH-III or sGnRH. GnRH-I and GnRH-II show similar potencies regarding gonadotropins secretion, intracellular IP3 production and Ca2+ mobilization, while sGnRH and gpGnRH are less potent. We do not detect any lGnRH-III physiologic response in rat pituitary cells. Furthermore, we propose a GnRHR different from the type-I receptor in rat ovarian SPO cells. This work demonstrates the existence of different GnRH systems in the rat, which could participate in the modulation of sexual behavior (eg. GnRH-II), autocrine/paracrine regulation of gonadotropic function and intra-ovaric modulation of gonadal physiology Fil: Mongiat, Lucas A.. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Recio Rubio, Lucía; Heras García de Vinuesa, Ana de las; Suárez-Fernández-Miranda, Susana; Córdoba-Roldán, Antonio; +1 Authors

    La presente investigación se enmarca dentro de la línea de investigación de innovación metodológica en los procesos de diseño y desarrollo de productos industriales, con enfoque en el usuario, con el objetivo de la formulación de una metodología de diseño emocional para el sector del automóvil, que toma como base la unión de la Ingeniería Kansei con la Neurociencia, permitiendo así incorporar las emociones de los usuarios como factor imprescindible en el proceso de diseño. Esta propuesta participa en la ampliación del concepto de ergonomía aplicada a productos y a entornos de trabajo, la cual ha evolucionado desde los conceptos de ergonomía clásica o ergonomía física hacia otros ámbitos relacionados con la incorporación e interacción emocional y racional del diseño. El objetivo final de la Ingeniería Kansei Chisei es establecer la relación entre emoción, razón y propiedades vehículo, de tal manera que los resultados puedan ser utilizados para mejorar el confort y la eficiencia del producto. This research is framed within the line of research of methodological innovation in the processes of design and development of industrial products, with a focus on the user, with the aim of formulating a methodology of emotional design for the automotive sector, which takes as its basis the union of Kansei Engineering with Neuroscience, thus allowing to incorporate the emotions of users as an essential factor in the design process. This proposal participates in the extension of the concept of ergonomics applied to products and work environments, which has evolved from the concepts of classic ergonomics or physical ergonomics to other areas related to the incorporation and emotional and rational interaction of design. The final objective of Kansei Chisei Engineering is to establish the relationship between emotion, reason and vehicle properties, in such a way that the results can be used to improve the comfort and efficiency of the product.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ idUS. Depósito de In...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ idUS. Depósito de In...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mazzadi, Alejandro N.;

    Se estudió la producción de calor (Ht) y evolución mecánica en ventrículos de rata estimulados electricamente a 1.5 Hz, perfundidos según la Técnica de Langendorff y sometidos a 45 min de isquemia (Isq) y 45 min de reperfusión (Rep). La influencia de la temperatura se evaluó a 25, 30 y 35 °C. Los 4 componentes diferenciables del calor activo (H1, H2, H3 y H4)(Ponce-Hornos y col, Pflugers Arch-Eur J Physiol 429; 1995) se analizaron en contracciones aisladas en los 10 primeros min de Isch. Los músculos se montaron en un calorímetro (Ponce-Hornos y col, Am. J. of Physiol. 243; 1982) que permitió medir Ht y simultaneamente la presión desarrollada en condiciones isovolúmicas (P) y la presión de reposo (PR). A partir de los estudios realizados fue posible descartar procesos que fueron postulados como responsables de la falla cardíaca isquémica e involucrar en medida apropiada a otros. Entre los primeros, fue posible descartar la caída del pH y los cambios en la energía libre del ATP como responsables en etapas muy tempranas. También pudo disociarse la caída de la P respecto de la desaparición de un componente mitocondrial Ca++ dependiente (H4). Entre los segundos, se identificó un evento energético durante la Isch de alto valor predictivo de la disfunción mecánica y/o daño durante la Rep. También, los experimentos dan apoyo a los cambios en la PR como responsables de la abrupta caída en la P al inicio de la Isch. Además, fué posible vincular a la interacción actomiosínica con la mayor fracción de liberación de energía en el período inicial de la Rep. También se asoció la baja recuperación mecánica durante la Rep con altos valores relativos de calor independiente de tensión. Total heat production and mechanical evolution were studied in electrically stimulated (1.5 Hz) rat's ventricles perfused by Langendorff technique and subjected to ischemia (Isch) and reperfusion(Rep) (45 min both). Temperature effect was evaluated at 25, 30 and 35 °C. Four identified active heat components from a single contraction (H1, H2, H3 and H4)(Ponce-Hornos et al, Pflugers Arch-Eur J. Physiol 429;1995)) were analyzed during the first 10 min of isch. Resting (RP) and developed pressure(P) and total heat production (Ht) were simultaneously measured on isovolumetric hearts placed in a calorimeter (Ponce-Hornos et al, Am J. of Physiol 243;1982). From these results a fall in pH, as well as changes in ATP free energy, were discarded as possible causes of cardiac failure after early isch. Also, the fall in developed pressure was dissociated from the Ca++-dependent mitochondrial component (H4). An energetic event was identified during the ischemic phase which was highly related with the mechanical failure during reperfusion. And the other hand, these experiments suggest that changes in RP are responsible for the brisk fall in P at the beginning of the isch. Even more, the main fraction of released energy during the beginning of Rep was associated to acto-myosin interaction. Finally, the small mechanical recovery during Rep was related with high relative values of tension independent heat.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Hyper Article en Ligne
    Other literature type . 1997
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Hyper Article en Ligne
      Other literature type . 1997
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Pons Rivero, Antonio Javier; García Ojalvo, Jordi;

    Peer Reviewed

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Recolector de Ciencia Abierta, RECOLECTA
    Other literature type . Article . 2012 . Peer-reviewed
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Recolector de Ciencia Abierta, RECOLECTA
      Other literature type . Article . 2012 . Peer-reviewed
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Vega, Antonny G.; Aguilar, Carlos R.; Barrientos, Alfredo; Villalta, Rosario;

    Personas con discapacidad motora presentan inconvenientes en el desarrollo de actividades tales como caminar, correr, comer. Además, en su mayoría, la visión y el intelecto no se ven afectados. Estas deficiencias no le permiten al manipular dispositivos tecnológicos que podrían ayudarlo a mejorar su calidad de vida como los smartphones. Presentamos una solución que permite superar esta limitación apoyada en la tecnología Brain Computer Interface).

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    ZENODO
    Article . 2018
    License: CC BY
    Data sources: Datacite
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    ZENODO
    Article . 2018
    License: CC BY
    Data sources: ZENODO
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    visibility24
    visibilityviews24
    downloaddownloads23
    Powered by Usage counts
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      ZENODO
      Article . 2018
      License: CC BY
      Data sources: Datacite
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      ZENODO
      Article . 2018
      License: CC BY
      Data sources: ZENODO
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Bastidas Manzano, Ana Belén;

    Propuesta/objetivos: El exponencial auge experimentado por el sector turístico en los últimos años tiene como contrapartida el surgimiento de problemáticas como la sobresaturación de los espacios públicos, conflictos con los residentes en núcleos turísticos, alta emisión de gases efecto invernadero o encarecimiento del nivel de vida. Con el objetivo de solventar algunas de estas disyuntivas, la investigación en turismo aboga recientemente por diseñar destinos turísticos inteligentes (DTI), esto es, espacios turísticos que integren la sostenibilidad, innovación, tecnología, accesibilidad y gobernanza como base de su estrategia de desarrollo. Esta tesis doctoral precisamente ofrece una perspectiva del estado actual de la investigación en esta disciplina, al tiempo que aporta un estudio bibliométrico sobre el auge de las ciudades inteligentes y su relación con los DTI. Además, desarrolla un experimento con herramientas neurocientíficas que permite identificar el origen psicológico de las potenciales diferencias entre destinos tradicionales e inteligentes. Diseño/Metodología/Enfoque: Para identificar los principales pilares de los DTI, su evolución y potenciales vías de desarrollo, esta tesis doctoral implementa un análisis bibliométrico exhaustivo junto a una revisión sistemática de los estudios publicados en los últimos 15 años en la base de datos Web of Science que versan sobre turismo inteligente. Además, dada la naturaleza automática e inconsciente de la toma de decisiones del turista, implementa un experimento que utiliza una técnica de neuroimagen, la resonancia magnética funcional (fMRI), como método de evaluación de los mecanismos cerebrales desencadenados por entornos de turismo inteligente en comparación con otros tradicionales. Hallazgos: Los resultados derivados de esta tesis doctoral avanzan: (i) la definición de los DTI y sus principales pilares, (ii) las iniciativas de mayor calado desarrolladas en destinos turísitcos inteligentes en España, (iii) las revistas científicas y autores que han evaluado el concepto de DTI, (iv) las potenciales vías de investigación que merecen ser abordadas en el futuro de los DTI; (v) el valor de la neurociencia como herramienta crucial en la identificación de los mecanismos psicológicos relacionados con la toma de decisiones del turista y, (vi) las diferencias neuropsicológicas derivadas de la evaluación de elementos propios de destinos tradicionales e inteligentes. Originalidad/Valor: Esta tesis doctoral es la primera que desarrolla la definición de DTI, los pilares fundamentales sobre los que se basa, los principales temas y subtemas estudiados hasta el momento, así como los autores y revistas más representativos en la literatura que aborda dicha disciplina. A la vez, identifica la contribución de los DTI a la mejora de las necesidades reales de los territorios y la experiencia turística. Más importante, se trata del primer trabajo de investigación que realiza una comparativa en la literatura entre las publicaciones de ciudades inteligentes y DTI. Además, esta tesis doctoral constituye la primera investigación que utiliza una técnica de neuroimagen, la fMRI, para identificar el origen neurológico de las actitudes e intenciones del turista hacia los destinos turísticos inteligentes. Proposal/Objectives: The exponential growth experienced by the tourism sector in recent years has been offset by the emergence of problems such as the over-saturation of public spaces, conflicts with residents in tourist areas, high emissions of greenhouse gases and rising living standards. With the aim of solving some of these dilemmas, tourism research recently advocated the design of smart tourism destinations (STD), i.e. tourism spaces that integrate sustainability, innovation, technology, accessibility, and governance as the basis of their development strategy. This doctoral thesis precisely offers a perspective on the current state of research in this discipline, while also providing a bibliometric study of the rise of smart cities and their relationship with smart tourist destinations. In addition, it develops an experiment with neuroscientific tools that allows identifying the psychological origin of the potential differences between traditional and smart destinations. Design/Methodology/Approach: In order to identify the main pillars of STD, their evolution and potential development paths, this doctoral thesis implements a comprehensive bibliometric analysis together with a systematic review of the studies published in the Web of Science database over the last 15 years that deal with smart tourism. Furthermore, given the automatic and unconscious nature of tourist decision making, it carries out an experimental design that uses a neuroimaging technique, functional magnetic resonance (fMRI), as a method of evaluating the brain mechanisms triggered by smart tourism environments in comparison with other traditional ones. Findings: The results derived from this doctoral thesis are progressing: (i) the definition of STDs and their main pillars, (ii) the most important initiatives developed in smart destinations in Spain, (iii) the scientific journals and authors who have evaluated the concept of STDs, (iv) the potential research paths that deserve to be addressed in the future of STDs; (v) the value of neuroscience as a crucial tool in the identification of psychological mechanisms related to tourist decision-making and, (vi) the neuropsychological differences derived from the evaluation of elements typical of traditional and smart destinations. Originality/Value: This doctoral thesis is the first to develop the definition of STD, the fundamental pillars on which it is based, the main themes and sub-themes studied so far, as well as the most representative authors and journals in the literature that addresses this discipline. At the same time, it identifies the contribution of STDs to the improvement of the real needs of the territories and the tourism experience. More importantly, this is the first research work that makes a comparison in the literature between smart cities and STDs. Furthermore, this doctoral thesis is the first research that makes use of a neuroimaging technique, fMRI, to identify the neurological origin of tourist attitudes and intentions towards smart tourist destinations. Fundación Ramón Areces Tesis Univ. Granada.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Sequeira Cordero, Andrey; Fornaguera Trías, Jaime;

    The study of individual differences in the forced swimming test (FST) in rats allows the identification of either susceptibility or resilience factors in the development of depression-related behaviors. In order to study these differences several rat groups were subjected to the FST. Afterward, animals with low and high immobility were compared, which allowed us to identify a number of features that could function as risk or protection factors. Thus, neurobiological factors such as the expression levels of the corticotropin-releasing factor receptor 1 (CRFR1) in the nucleus accumbens, a differential accumbal dopamine turnover and the differential expression kinetics of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex, could play an important role in the modulation of depressive behaviors. The current review summarizes our key results in such research line. El estudio de las diferencias individuales en la prueba de nado forzado (PNF) en ratas permite la identificación de factores de susceptibilidad o de resistencia en el desarrollo conductas relacionadas con la depresión. Para estudiar estas diferencias, varios grupos de ratas fueron sometidos a la PNF; posteriormente, los animales con baja y alta inmovilidad fueron comparados, lo que permitió identificar una serie de características que podrían estar actuando como factores de riesgo o de protección. Así, factores neurobiológicos como la expresión diferencial en el núcleo accumbens del receptor 1 para el factor liberador de corticotropina (CRFR1), una tasa diferencial de recambio de dopamina en esa misma región y la cinética de expresión diferencial del factor neurotrófico derivado del cerebro (BDNF) en la corteza prefrontal, podrían jugar un papel importante en la modulación de conductas depresivas. La presente revisión resume nuestros resultados más importantes en esta línea de investigación.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ LAReferencia - Red F...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ LAReferencia - Red F...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Schmitt, Andrea; Otto, Sylvia; Jatzko, Alexander; Ruf, Matthias; +6 Authors

    OBJECTIVES: In first-episode schizophrenia patients, functional magnetic resonance imaging (fMRI) has shown prefronto-parietal dysfunction during acoustic and visual stimulation. The aim of this study was to investigate the prefronto-parietal network in elderly schizophrenia patients using the same paradigm. Additionally, we hypothesized favourable effects on brain activation by the atypical antipsychotic clozapine compared to typical neuroleptics. METHODS: We investigated 18 elderly, chronic schizophrenia patients and 21 elderly healthy controls. Nine schizophrenia patients had been medicated with clozapine and 9 had been receiving typical neuroleptics over decades. In addition to assessments with psychopathological and neuropsychological rating scales we used an acoustic and visual stimulation paradigm in a 1.5 Tesla MRI scanner to investigate BOLD-response in different brain areas. RESULTS: Compared to healthy controls schizophrenia patients showed decreased brain activation in the prefrontal and parietal cortex as well as medial anterior cingulate gyrus compared to healthy controls. In these regions, patients medicated with clozapine showed increased BOLD-response compared to patients treated with typical neuroleptics. DISCUSSION: Our study confirmed prefronto-parietal network disturbances in elderly schizophrenia patients thus pointing to the preservation of brain activation deficits and the influence of neurodevelopmental disturbances in chronic schizophrenia until old-age. CONCLUSION: The atypical antipsychotic clozapine seems to facilitate brain activation even in elderly, chronic schizophrenia patients. OBJETIVOS: Em pacientes com primeiro episódio de esquizofrenia, estudos com ressonância magnética funcional (RMf) têm demonstrado disfunção pré-frontoparietal durante estimulação acústica e visual. O objetivo do presente estudo foi investigar a rede pré-frontoparietal em pacientes idosos com esquizofrenia utilizando o mesmo paradigma. Adicionalmente, foram presumidos efeitos favoráveis na ativação cerebral pelo antipsicótico atípico clozapina em comparação a neurolépticos típicos. MÉTODOS: Foram investigados 18 pacientes com esquizofrenia crônica e 21 controles saudáveis idosos. Nove pacientes com esquizofrenia haviam sido medicados com clozapina e nove haviam recebido neurolépticos típicos por décadas. Concomitantemente às avaliações com escalas psicopatológicas e neuropsicológicas foi utilizado um paradigma de estimulação auditiva e visual em um aparelho de ressonância magnética de 1,5 Tesla para investigar a resposta BOLD em diferentes áreas cerebrais. RESULTADOS: Comparados a controles saudáveis, os pacientes com esquizofrenia apresentaram diminuição na ativação cerebral nos córtices pré-frontal e parietal, assim como no giro do cíngulo anterior medial. Nessas regiões, os pacientes medicados com clozapina apresentaram resposta BOLD aumentada em comparação aos pacientes tratados com neurolépticos típicos. DISCUSSÃO: O presente estudo confirmou a presença de distúrbios na rede pré-frontoparietal em pacientes idosos com esquizofrenia, apontando assim para a preservação de déficits de ativação cerebrais e a influência de distúrbios do desenvolvimento neural em esquizofrenia crônica até a velhice. CONCLUSÃO: O antipsicótico atípico clozapina parece facilitar a ativação de áreas cerebrais mesmo em pacientes idosos com esquizofrenia crônica.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Göttingen Research O...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Castillo Silva, Flavio de Jesús;

    Resumen: El presente artículo hace un recuento de los andragogos que han aportado para la construcción de la Andragogía, que como ciencia incipiente, tiene aún muchas oportunidades de mejora para que los adultos estén en una situación de libertad en sus procesos de aprendizajes. Abstract: The present article makes a recount of the andragogists that have contributed for the construction of the Andragogy, that as incipient science, still has many opportunities of improvement so that the adults are in a situation of freedom in their learning processes.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    ZENODO
    Article . 2018
    License: CC BY
    Data sources: ZENODO
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Hyper Article en Ligne
    Other literature type . 2018
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    DOAJ
    Article . 2018
    Data sources: DOAJ
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Voces de la educación
    Article . 2018
    Data sources: DOAJ-Articles
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    ZENODO
    Article . 2018
    License: CC BY
    Data sources: Datacite
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    1
    citations1
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    visibility622
    visibilityviews622
    downloaddownloads303
    Powered by Usage counts
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      ZENODO
      Article . 2018
      License: CC BY
      Data sources: ZENODO
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Hyper Article en Ligne
      Other literature type . 2018
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      DOAJ
      Article . 2018
      Data sources: DOAJ
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Voces de la educación
      Article . 2018
      Data sources: DOAJ-Articles
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      ZENODO
      Article . 2018
      License: CC BY
      Data sources: Datacite
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
search
The following results are related to Neuroinformatics. Are you interested to view more results? Visit OpenAIRE - Explore.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Noriega Puente, Andrea;

    RESUMEN: El glioma es el tipo de tumor cerebral más común, presentando distintos grados de malignidad y agresividad, así como un pronóstico variable. La gran variabilidad que caracteriza a estas lesiones implica un estudio completamente único, así como un tratamiento personalizado. Es por esto que la segmentación manual de este tipo de lesiones supone tanto un gran consumo de tiempo como un trabajo duro para el experto, el cual implica el análisis multimodal de varias secuencias diferentes, normalmente, de Resonancia Magnética. En este trabajo se presenta un modelo de segmentación automática de gliomas de alto grado, HGG, cuya arquitectura se basa en el empleo de redes neuronales convolucionales simétricas, denominada U-Net. Para el entrenamiento del modelo se ha hecho uso del conjunto de datos del Data Challenge BraTS 2018 (Brain Tumor Segmentation), compuesto por un total de 237 estudios de IRM, 162 HGG y 75 LGG, de los que solo se han empleado los primeros. Los resultados en cuanto a la obtención de mapas binarios de segmentación de los tumores han sido positivos. Se ha calculado el coeficiente DICE medio, relacionado con la calidad de la determinación de la forma del tumor, logrando 0:64 +- 0:39 para el modelo entrenado con imágenes T1, y 0:57 +- 0:41 para el modelo entrenado con secuencias T1 con contraste. Cualitativamente se ha observado además un buen desempeño a la hora de localizar espacialmente los tumores, incluso si la forma no es determinada tan precisamente. ABSTRACT: Glioma is the most common type of brain tumor, having di_erent degrees of malignancy and aggressiveness, as well as a variable prognosis. The great variability of these pathologies implies a completely unique study, as well as a personalized treatment. This is why the manual segmentation of brain tumors by an expert entails both a big time consumption and a really hard work, involving the multimodal analysis of several different sequences of Magnetic Resonance. In this project, an automatic segmentation model of high-grade glioma, HGG, is introduced, whose architecture is based in symmetric convolutional neural networks, called U-Net. For training the model, data from the Data Challenge BraTS 2018 (Brain Tumor Segmentation) have been used, consisting of a total of 237 MRI studies, 162 HGG cases and 75 LGG cases, from which only the first ones have been used. Resulting binary segmentation map of the tumors have been positive. The mean DICE coe_cient, related to the quality of tumor shape determination, has been calculated, achieving 0:64 +- 0:39 for the model trained with T1 sequences, and 0:57 +- 0:41 for the model trained with T1 enhanced sequences. Qualitatively, good performance has also been observed when determining spatial location of the tumors, even if the shape is not determined so precisely. Máster en Ciencia de Datos

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ UCreaarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    UCrea
    Master thesis . 2019
    License: CC BY NC ND
    Data sources: UCrea
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ UCreaarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      UCrea
      Master thesis . 2019
      License: CC BY NC ND
      Data sources: UCrea
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mongiat, Lucas A.;

    A la fecha, se conocen 24 variantes de la Hormona Liberadora de Gonadotrofinas (GnRH). Se ha demostrado en numerosos vertebrados,incluyendo mamíferos, que más de una variante de GnRH son expresadas en una misma especie. En la rata existen evidencias postulando la presencia de diferentes variantes de GnRH, conjuntamente con la ya caracterizada GnRH-I, ellas son: GnRH-II, gpGnRH, sGnRH y lGnRH-III. Por otro lado, se demostró la presencia de más de un receptor de GnRH (GnRHR) en distintas especies. Sin embargo, en un modelo ampliamente utilizado como lo es la rata, hay controversia acerca de los sistemas de GnRH presentes. El objetivo de esta Tesis, consiste en estudiar los distintos sistemas de GnRH presentes en rata. En este trabajo estudiamos extractos peptídicos de distintos tejidos mediante diferentes sistemas de RP-HPLC conjugado con detección con distintos RIA para GnRH, determinamos la actividad biológica de las diferentes variantes postuladas en rata y abordamos la búsqueda de un receptor diferente del conocido GnRHR tipo-I. Concluimos que, la actividad gonadotrófica hipofisaria parece estar mediada por el sistema GnRH-I/GnRHR tipo I. Demostramos la presencia de HypGnRH, aportamos fuertes evidencias de la expresión de GnRH-II en cerebro e hipófisis y postulamos la presencia de gpGnRH. No encontramos evidencias de la expresión de lGnRH-III o sGnRH. Establecimos que GnRH-I y GnRH-II poseen similares potencias en cuanto a su actividad hipofisaria, mientras que sGnRH y gpGnRH poseen una menor potencia. No detectamos efectos fisiológicos de lGnRH-III en células hipofisarias. Proponemos la existencia en células ováricas de un sitio de unión a GnRH diferente del expresado en hipófisis. Este trabajo evidencia la existencia de distintos sistemas de GnRH presentes en rata. Estos sistemas podrían participar en diferentes funciones como ser la modulación de la conducta sexual (ej GnRH-II), la regulación autócrina/parácrina de la respuesta gonadotrófica hipofisaria, regulación intra-ovárica de la función gonadal. To date, 24 Gonadotropin Releasing Hormone (GnRH) variants have been described. In several vertebrates, including mammals, more than one GnRH variant are co-expressed in a single species. In the rat, there are evidences postulating various GnRH variants, together with GnRH-I, they are: GnRH-II, gpGnRH, sGnRH and lGnRH-III. On the other hand, different receptors for this hormone have been demonstrated in several species. However, in such an important model as the rat, there is controversy regarding the GnRH systems present. The aim of this Thesis was to study the different GnRH systems in the rat. Here, we characterize peptidic extracts from rat tissues by different RP-HPLC systems together with GnRH RIA detection; we study the biologic activity of the GnRH variants postulated to be present in rat and examine the possible existence of a receptor distinct from the already known type-I GnRHR. We conclude that gonadotropic activity in the rat is mediated by the GnRH-I/type-I GnRHR system. In addition, we demonstrate the expression of hypGnRH, provide strong evidences for GnRH-II presence in brain and pituitary and show experimental data supporting gpGnRH existence in the rat. However, we do not detect either lGnRH-III or sGnRH. GnRH-I and GnRH-II show similar potencies regarding gonadotropins secretion, intracellular IP3 production and Ca2+ mobilization, while sGnRH and gpGnRH are less potent. We do not detect any lGnRH-III physiologic response in rat pituitary cells. Furthermore, we propose a GnRHR different from the type-I receptor in rat ovarian SPO cells. This work demonstrates the existence of different GnRH systems in the rat, which could participate in the modulation of sexual behavior (eg. GnRH-II), autocrine/paracrine regulation of gonadotropic function and intra-ovaric modulation of gonadal physiology Fil: Mongiat, Lucas A.. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Recio Rubio, Lucía; Heras García de Vinuesa, Ana de las; Suárez-Fernández-Miranda, Susana; Córdoba-Roldán, Antonio; +1 Authors

    La presente investigación se enmarca dentro de la línea de investigación de innovación metodológica en los procesos de diseño y desarrollo de productos industriales, con enfoque en el usuario, con el objetivo de la formulación de una metodología de diseño emocional para el sector del automóvil, que toma como base la unión de la Ingeniería Kansei con la Neurociencia, permitiendo así incorporar las emociones de los usuarios como factor imprescindible en el proceso de diseño. Esta propuesta participa en la ampliación del concepto de ergonomía aplicada a productos y a entornos de trabajo, la cual ha evolucionado desde los conceptos de ergonomía clásica o ergonomía física hacia otros ámbitos relacionados con la incorporación e interacción emocional y racional del diseño. El objetivo final de la Ingeniería Kansei Chisei es establecer la relación entre emoción, razón y propiedades vehículo, de tal manera que los resultados puedan ser utilizados para mejorar el confort y la eficiencia del producto. This research is framed within the line of research of methodological innovation in the processes of design and development of industrial products, with a focus on the user, with the aim of formulating a methodology of emotional design for the automotive sector, which takes as its basis the union of Kansei Engineering with Neuroscience, thus allowing to incorporate the emotions of users as an essential factor in the design process. This proposal participates in the extension of the concept of ergonomics applied to products and work environments, which has evolved from the concepts of classic ergonomics or physical ergonomics to other areas related to the incorporation and emotional and rational interaction of design. The final objective of Kansei Chisei Engineering is to establish the relationship between emotion, reason and vehicle properties, in such a way that the results can be used to improve the comfort and efficiency of the product.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ idUS. Depósito de In...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ idUS. Depósito de In...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Mazzadi, Alejandro N.;

    Se estudió la producción de calor (Ht) y evolución mecánica en ventrículos de rata estimulados electricamente a 1.5 Hz, perfundidos según la Técnica de Langendorff y sometidos a 45 min de isquemia (Isq) y 45 min de reperfusión (Rep). La influencia de la temperatura se evaluó a 25, 30 y 35 °C. Los 4 componentes diferenciables del calor activo (H1, H2, H3 y H4)(Ponce-Hornos y col, Pflugers Arch-Eur J Physiol 429; 1995) se analizaron en contracciones aisladas en los 10 primeros min de Isch. Los músculos se montaron en un calorímetro (Ponce-Hornos y col, Am. J. of Physiol. 243; 1982) que permitió medir Ht y simultaneamente la presión desarrollada en condiciones isovolúmicas (P) y la presión de reposo (PR). A partir de los estudios realizados fue posible descartar procesos que fueron postulados como responsables de la falla cardíaca isquémica e involucrar en medida apropiada a otros. Entre los primeros, fue posible descartar la caída del pH y los cambios en la energía libre del ATP como responsables en etapas muy tempranas. También pudo disociarse la caída de la P respecto de la desaparición de un componente mitocondrial Ca++ dependiente (H4). Entre los segundos, se identificó un evento energético durante la Isch de alto valor predictivo de la disfunción mecánica y/o daño durante la Rep. También, los experimentos dan apoyo a los cambios en la PR como responsables de la abrupta caída en la P al inicio de la Isch. Además, fué posible vincular a la interacción actomiosínica con la mayor fracción de liberación de energía en el período inicial de la Rep. También se asoció la baja recuperación mecánica durante la Rep con altos valores relativos de calor independiente de tensión. Total heat production and mechanical evolution were studied in electrically stimulated (1.5 Hz) rat's ventricles perfused by Langendorff technique and subjected to ischemia (Isch) and reperfusion(Rep) (45 min both). Temperature effect was evaluated at 25, 30 and 35 °C. Four identified active heat components from a single contraction (H1, H2, H3 and H4)(Ponce-Hornos et al, Pflugers Arch-Eur J. Physiol 429;1995)) were analyzed during the first 10 min of isch. Resting (RP) and developed pressure(P) and total heat production (Ht) were simultaneously measured on isovolumetric hearts placed in a calorimeter (Ponce-Hornos et al, Am J. of Physiol 243;1982). From these results a fall in pH, as well as changes in ATP free energy, were discarded as possible causes of cardiac failure after early isch. Also, the fall in developed pressure was dissociated from the Ca++-dependent mitochondrial component (H4). An energetic event was identified during the ischemic phase which was highly related with the mechanical failure during reperfusion. And the other hand, these experiments suggest that changes in RP are responsible for the brisk fall in P at the beginning of the isch. Even more, the main fraction of released energy during the beginning of Rep was associated to acto-myosin interaction. Finally, the small mechanical recovery during Rep was related with high relative values of tension independent heat.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Hyper Article en Ligne
    Other literature type . 1997
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital (...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Hyper Article en Ligne
      Other literature type . 1997
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Pons Rivero, Antonio Javier; García Ojalvo, Jordi;

    Peer Reviewed

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Recolector de Ciencia Abierta, RECOLECTA
    Other literature type . Article . 2012 . Peer-reviewed
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    addClaim

    This Research product is the result of merged Research products in OpenAIRE.

    You have already added works in your ORCID record related to the merged Research product.
    0
    citations0
    popularityAverage
    influenceAverage
    impulseAverage
    BIP!Powered by BIP!
    more_vert
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Recolector de Ciencia Abierta, RECOLECTA
      Other literature type . Article . 2012 . Peer-reviewed
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      addClaim

      This Research product is the result of merged Research products in OpenAIRE.

      You have already added works in your ORCID record related to the merged Research product.