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  • Neuroinformatics
  • 2014-2023

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  • Authors: Gadbin, Daniel;
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  • Authors: Blondeau, Virginie; Poulain, Xavier; Trémeau, Élise; Daloz, Amélie;

    Henri, fils de mineur, et Martial, ancien mineur, nous font part de la vie à l'époque des mines de charbon qu'ils ont tous deux côtoyée.

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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Davide Clemente; Leonardo Davì; Ettore De Monte;

    To verify the usefulness of visual stimulation in CBT techniques or systematic desensitization and flooding, through the study of neurocognitive responses (ERPs) to specific and repetitive phobic or neutral stimuli, in patients with specific phobias. The study involved 2 groups, both composed of 20 subjects: an experimental group and a control group. Slideshows consist of randomized phobic images, whose characteristics are personalized for the specific phobia, and neutral images identical for all subjects. The ERPs recorded during visual stimulation were analyzed, distinguishing the potentials generated by phobic and neutral stimulations. The ERPs present typical waves (P1, P2, P3a, and P3b) that represent the cortical processing of the image. The study shows, in phobic subjects with specific phobic stimuli, an increase in P2 component amplitude due to greater activation of cortical networks by emotional response and the increase in amplitude of P3b component compared with the control group, probably in relation to looking for specific details of the phobic image. It is interesting to note that P3b component tends to regress during repetitive stimulation. The study showed that, through digital stimulation, phobic patients become accustomed to the presentation of phobic stimuli with an average decrease of 12–13% in P2 and an average reduction of 25% in N2. This result allows the hypothesis that this stimulation is useful to replace stimulation in vivo, or as a preparation for it. The variation of the potential evoked during the stimulation can help the therapist modulate the stimulation itself. The authors also propose to continue the development of this research also using the development of augmented reality (VR).

    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Technolog...arrow_drop_down
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Journal of Technology in Behavioral Science
    Article . 2019 . Peer-reviewed
    License: Springer TDM
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Technolog...arrow_drop_down
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      Journal of Technology in Behavioral Science
      Article . 2019 . Peer-reviewed
      License: Springer TDM
      Data sources: Crossref
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  • Authors: Krommenacker, Nicolas; Tran-Dang, Hoa; Charpentier, Patrick;

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  • Authors: Piette, Albert;

    L’auteur définit l’anthropologie existentiale comme une observation des existences présentes dans une situation, venant d’autres situations et continuant à se déplacer vers de nouvelles situations. D’une part, l’article insiste sur l’importance d’une méthodologie détailliste consistant à suivre des individus, plus précisément un individu à la fois au fil des moments. L’auteur préfère le terme phénoménographie à celui d’ethnographie, pour désigner cette focalisation détaillée sur des individus séparés. D’autre part, en débat avec les sciences sociales, l’auteur insiste sur la subtilité des modes de présence des individus, les parts de latéralité qu’ils contiennent, ainsi que sur la singularité de chacun. Dans cette perspective, la vigilance est au coeur d’une anthropologie des existences.

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  • Authors: Patrick, Aldrin-Kirk; Tomas, Björklund;

    Chemogenetics is the process of genetically expressing a macromolecule receptor capable of modulating the activity of the cell in response to selective chemical ligand. This chapter will cover the chemogenetic technologies that are available to date, focusing on the commonly available engineered or otherwise modified ligand-gated ion channels and G-protein-coupled receptors in the context of neuromodulation. First, we will give a brief overview of each chemogenetic approach as well as in vitro/in vivo applications, then we will list their strengths and weaknesses. Finally, we will provide tips for ligand application in each case.Each technology has specific limitations that make them more or less suitable for different applications in neuroscience although we will focus mainly on the most commonly used and versatile family named designer receptors exclusively activated by designer drugs or DREADDs. We here describe the most common cases where these can be implemented and provide tips on how and where these technologies can be applied in the field of neuroscience.

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    Authors: Guiheux, Gilles;

    Les migrations massives de populations rurales vers les villes chinoises constituent l'un des faits sociaux majeurs de la fin du XXe siècle et du début du XXIe siècle. Alors que le régime communiste avait organisé et institutionnaliséunefrontière entre villes et campagnes, notamment par le biais du système d'enregistrement des ménages, celui-ci, sans pour autant disparaître, s'est assoupli.La société chinoise, jusque-là largement immobile, où les statuts et les positions étaient hérités ou assignés par des décisions politiques, s'est ainsi remise en mouvement. Les villes chinoises, qu'elles soient pluri-millionnaires, de taille intermédiaire ou petites, comptent désormais une population récemment installée qui peut représenter la moitié ou les deux tiers de la population totale. Ce brassage a pris la forme de multiples déplacements dans l'espace national comme dans l'espace social. Ce phénomène migratoire mérite que Shi Lu y consacre un ouvrage non seulement par son ampleur inégalée dans l'histoire de l'humanité, mais aussi par le défi qu'il pose aux sciences sociales.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Hyper Article en Lig...arrow_drop_down
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    Other literature type . 2014
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Hyper Article en Lig...arrow_drop_down
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      Other literature type . 2014
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    Authors: Padilla, Arturo;

    Les travaux présentés dans ce mémoire traitent de l'identification des systèmes dynamiques représentés sous la forme de modèles linéaires continus à paramètres variant lentement au cours du temps. La complexité du problème d'identification provient d'une part du caractère inconnu de la loi de variation des paramètres et d'autre part de la présence de bruits de nature inconnue sur les signaux mesurés. Les solutions proposées s'appuient sur une combinaison judicieuse du filtre de Kalman en supposant que les variations des paramètres peuvent être représentées sous la forme d'une marche aléatoire et de la méthode de la variable instrumentale qui présente l'avantage d'être robuste vis à vis de la nature des bruits de mesure. Les algorithmes de type récursif sont développés dans un contexte d'identification en boucle ouverte et en boucle fermée. Les différentes variantes se distinguent par la manière dont est construit la variable instrumentale. Inspirée de la solution développée pour les systèmes linéaires à temps invariant, une construction adaptative de la variable instrumentale est suggérée pour pouvoir suivre au mieux l'évolution des paramètres. Les performances des méthodes développées sont évaluées à l'aide de simulations de Monte Carlo et montrent la suprématie des solutions proposées s'appuyant sur la variable instrumentale par rapport celles plus classiques des moindres carrés récursifs. Les aspects pratiques et d'implantation numérique sont d'une importance capitale pour obtenir de bonnes performances lorsque ces estimateurs sont embarqués. Ces aspects sont étudiés en détails et plusieurs solutions sont proposées non seulement pour robustifier les estimateurs vis à vis du choix des hyper-paramètres mais également vis à vis de leur implantation numérique. Les algorithmes développés sont venus enrichir les fonctions de la boîte à outils CONTSID pour Matlab. Enfin, les estimateurs développés sont exploités pour faire le suivi de paramètres de deux systèmes physiques : un benchmark disponible dans la littérature constitué d'un filtre électronique passe-bande et une vanne papillon équipant les moteurs de voiture. Les deux applications montrent le potentiel des approches proposées pour faire le suivi de paramètres physiques variant lentement dans le temps The work presented in this thesis deals with the identification of dynamic systems represented through continuous-time linear models with slowly time-varying parameters. The complexity of the identification problem comes on the one hand from the unknown character of the parameter variations and on the other hand from the presence of noises of unknown nature on the measured signals. The proposed solutions rely on a judicious combination of the Kalman filter assuming that the variations of the parameters can be represented in the form of a random walk, and the method of the instrumental variable which has the advantage of being robust with respect to the nature of the measurement noises. The recursive algorithms are developed in an open-loop and closed-loop identification setting. The different variants are distinguished by the way in which the instrumental variable is built. Inspired by the solution developed for time-invariant linear systems, an adaptive construction of the instrumental variable is suggested in order to be able to follow the evolution of the parameters as well as possible. The performance of the developed methods are evaluated using Monte Carlo simulations and show the supremacy of the proposed solutions based on the instrumental variable compared with the more classical least squares based approaches. The practical aspects and implementation issues are of paramount importance to obtain a good performance when these estimators are used. These aspects are studied in detail and several solutions are proposed not only to robustify the estimators with respect to the choice of hyperparameters but also with respect to their numerical implementation. The algorithms developed have enhanced the functions of the CONTSID toolbox for Matlab. Finally, the developed estimators are considered in order to track parameters of two physical systems: a benchmark available in the literature consisting of a bandpass electronic filter and a throttle valve equipping the car engines. Both applications show the potential of the proposed approaches to track physical parameters that vary slowly over time

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Hyper Article en Lig...arrow_drop_down
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    Other literature type . 2017
    Hal-Diderot
    Doctoral thesis . 2017
    Data sources: Hal-Diderot
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Hyper Article en Lig...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Hyper Article en Ligne
      Other literature type . 2017
      Hal-Diderot
      Doctoral thesis . 2017
      Data sources: Hal-Diderot
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Bonnin, Grégory;

    International audience; no abstract

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Oskar Bordeauxarrow_drop_down
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    Oskar Bordeaux
    Part of book or chapter of book . 2014
    Data sources: Oskar Bordeaux
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  • Authors: Moizard, Nicolas; Brockmann, Judith;
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The following results are related to Neuroinformatics. Are you interested to view more results? Visit OpenAIRE - Explore.
714,732 Research products
  • Authors: Gadbin, Daniel;
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  • Authors: Blondeau, Virginie; Poulain, Xavier; Trémeau, Élise; Daloz, Amélie;

    Henri, fils de mineur, et Martial, ancien mineur, nous font part de la vie à l'époque des mines de charbon qu'ils ont tous deux côtoyée.

    0
    citations0
    popularityAverage
    influenceAverage
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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Davide Clemente; Leonardo Davì; Ettore De Monte;

    To verify the usefulness of visual stimulation in CBT techniques or systematic desensitization and flooding, through the study of neurocognitive responses (ERPs) to specific and repetitive phobic or neutral stimuli, in patients with specific phobias. The study involved 2 groups, both composed of 20 subjects: an experimental group and a control group. Slideshows consist of randomized phobic images, whose characteristics are personalized for the specific phobia, and neutral images identical for all subjects. The ERPs recorded during visual stimulation were analyzed, distinguishing the potentials generated by phobic and neutral stimulations. The ERPs present typical waves (P1, P2, P3a, and P3b) that represent the cortical processing of the image. The study shows, in phobic subjects with specific phobic stimuli, an increase in P2 component amplitude due to greater activation of cortical networks by emotional response and the increase in amplitude of P3b component compared with the control group, probably in relation to looking for specific details of the phobic image. It is interesting to note that P3b component tends to regress during repetitive stimulation. The study showed that, through digital stimulation, phobic patients become accustomed to the presentation of phobic stimuli with an average decrease of 12–13% in P2 and an average reduction of 25% in N2. This result allows the hypothesis that this stimulation is useful to replace stimulation in vivo, or as a preparation for it. The variation of the potential evoked during the stimulation can help the therapist modulate the stimulation itself. The authors also propose to continue the development of this research also using the development of augmented reality (VR).

    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Technolog...arrow_drop_down
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Journal of Technology in Behavioral Science
    Article . 2019 . Peer-reviewed
    License: Springer TDM
    Data sources: Crossref
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal of Technolog...arrow_drop_down
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      Journal of Technology in Behavioral Science
      Article . 2019 . Peer-reviewed
      License: Springer TDM
      Data sources: Crossref
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  • Authors: Krommenacker, Nicolas; Tran-Dang, Hoa; Charpentier, Patrick;

    National audience

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  • Authors: Piette, Albert;

    L’auteur définit l’anthropologie existentiale comme une observation des existences présentes dans une situation, venant d’autres situations et continuant à se déplacer vers de nouvelles situations. D’une part, l’article insiste sur l’importance d’une méthodologie détailliste consistant à suivre des individus, plus précisément un individu à la fois au fil des moments. L’auteur préfère le terme phénoménographie à celui d’ethnographie, pour désigner cette focalisation détaillée sur des individus séparés. D’autre part, en débat avec les sciences sociales, l’auteur insiste sur la subtilité des modes de présence des individus, les parts de latéralité qu’ils contiennent, ainsi que sur la singularité de chacun. Dans cette perspective, la vigilance est au coeur d’une anthropologie des existences.

    addClaim

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  • Authors: Patrick, Aldrin-Kirk; Tomas, Björklund;

    Chemogenetics is the process of genetically expressing a macromolecule receptor capable of modulating the activity of the cell in response to selective chemical ligand. This chapter will cover the chemogenetic technologies that are available to date, focusing on the commonly available engineered or otherwise modified ligand-gated ion channels and G-protein-coupled receptors in the context of neuromodulation. First, we will give a brief overview of each chemogenetic approach as well as in vitro/in vivo applications, then we will list their strengths and weaknesses. Finally, we will provide tips for ligand application in each case.Each technology has specific limitations that make them more or less suitable for different applications in neuroscience although we will focus mainly on the most commonly used and versatile family named designer receptors exclusively activated by designer drugs or DREADDs. We here describe the most common cases where these can be implemented and provide tips on how and where these technologies can be applied in the field of neuroscience.

    addClaim

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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Guiheux, Gilles;

    Les migrations massives de populations rurales vers les villes chinoises constituent l'un des faits sociaux majeurs de la fin du XXe siècle et du début du XXIe siècle. Alors que le régime communiste avait organisé et institutionnaliséunefrontière entre villes et campagnes, notamment par le biais du système d'enregistrement des ménages, celui-ci, sans pour autant disparaître, s'est assoupli.La société chinoise, jusque-là largement immobile, où les statuts et les positions étaient hérités ou assignés par des décisions politiques, s'est ainsi remise en mouvement. Les villes chinoises, qu'elles soient pluri-millionnaires, de taille intermédiaire ou petites, comptent désormais une population récemment installée qui peut représenter la moitié ou les deux tiers de la population totale. Ce brassage a pris la forme de multiples déplacements dans l'espace national comme dans l'espace social. Ce phénomène migratoire mérite que Shi Lu y consacre un ouvrage non seulement par son ampleur inégalée dans l'histoire de l'humanité, mais aussi par le défi qu'il pose aux sciences sociales.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Hyper Article en Lig...arrow_drop_down
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    Hyper Article en Ligne
    Other literature type . 2014
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      Other literature type . 2014
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    Authors: Padilla, Arturo;

    Les travaux présentés dans ce mémoire traitent de l'identification des systèmes dynamiques représentés sous la forme de modèles linéaires continus à paramètres variant lentement au cours du temps. La complexité du problème d'identification provient d'une part du caractère inconnu de la loi de variation des paramètres et d'autre part de la présence de bruits de nature inconnue sur les signaux mesurés. Les solutions proposées s'appuient sur une combinaison judicieuse du filtre de Kalman en supposant que les variations des paramètres peuvent être représentées sous la forme d'une marche aléatoire et de la méthode de la variable instrumentale qui présente l'avantage d'être robuste vis à vis de la nature des bruits de mesure. Les algorithmes de type récursif sont développés dans un contexte d'identification en boucle ouverte et en boucle fermée. Les différentes variantes se distinguent par la manière dont est construit la variable instrumentale. Inspirée de la solution développée pour les systèmes linéaires à temps invariant, une construction adaptative de la variable instrumentale est suggérée pour pouvoir suivre au mieux l'évolution des paramètres. Les performances des méthodes développées sont évaluées à l'aide de simulations de Monte Carlo et montrent la suprématie des solutions proposées s'appuyant sur la variable instrumentale par rapport celles plus classiques des moindres carrés récursifs. Les aspects pratiques et d'implantation numérique sont d'une importance capitale pour obtenir de bonnes performances lorsque ces estimateurs sont embarqués. Ces aspects sont étudiés en détails et plusieurs solutions sont proposées non seulement pour robustifier les estimateurs vis à vis du choix des hyper-paramètres mais également vis à vis de leur implantation numérique. Les algorithmes développés sont venus enrichir les fonctions de la boîte à outils CONTSID pour Matlab. Enfin, les estimateurs développés sont exploités pour faire le suivi de paramètres de deux systèmes physiques : un benchmark disponible dans la littérature constitué d'un filtre électronique passe-bande et une vanne papillon équipant les moteurs de voiture. Les deux applications montrent le potentiel des approches proposées pour faire le suivi de paramètres physiques variant lentement dans le temps The work presented in this thesis deals with the identification of dynamic systems represented through continuous-time linear models with slowly time-varying parameters. The complexity of the identification problem comes on the one hand from the unknown character of the parameter variations and on the other hand from the presence of noises of unknown nature on the measured signals. The proposed solutions rely on a judicious combination of the Kalman filter assuming that the variations of the parameters can be represented in the form of a random walk, and the method of the instrumental variable which has the advantage of being robust with respect to the nature of the measurement noises. The recursive algorithms are developed in an open-loop and closed-loop identification setting. The different variants are distinguished by the way in which the instrumental variable is built. Inspired by the solution developed for time-invariant linear systems, an adaptive construction of the instrumental variable is suggested in order to be able to follow the evolution of the parameters as well as possible. The performance of the developed methods are evaluated using Monte Carlo simulations and show the supremacy of the proposed solutions based on the instrumental variable compared with the more classical least squares based approaches. The practical aspects and implementation issues are of paramount importance to obtain a good performance when these estimators are used. These aspects are studied in detail and several solutions are proposed not only to robustify the estimators with respect to the choice of hyperparameters but also with respect to their numerical implementation. The algorithms developed have enhanced the functions of the CONTSID toolbox for Matlab. Finally, the developed estimators are considered in order to track parameters of two physical systems: a benchmark available in the literature consisting of a bandpass electronic filter and a throttle valve equipping the car engines. Both applications show the potential of the proposed approaches to track physical parameters that vary slowly over time

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    Other literature type . 2017
    Hal-Diderot
    Doctoral thesis . 2017
    Data sources: Hal-Diderot
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