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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Journal de Mycologie...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Journal de Mycologie Médicale
Article . 2008 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Hal-Diderot
Article . 2008
Data sources: Hal-Diderot
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Antifungal activity of aqueous and methanolic extracts from the Mediterranean sea cucumber, Holothuria polii

Authors: Ismail, H.; Lemriss, S.; Ben Aoun, Z.; Mhadhebi, L.; Dellai, A.; Kacem, Y.; Boiron, P.; +1 Authors

Antifungal activity of aqueous and methanolic extracts from the Mediterranean sea cucumber, Holothuria polii

Abstract

Abstract Crude extracts and semi-purified fractions (F5, F6) from the Mediterranean sea cucumber, Holothuria polii , collected from the bay of Tabarka (Tunisia coast) were evaluated for their antifungal activity against filamentous fungi and yeast. The activity was determined in vitro, using the well diffusion test in the casitone agar medium. Both the aqueous and the methanolic extracts were found to produce, in a concentration-related manner (600–1500 μg/well) a significant antifungal activity. The semi-purified fractions (F5, F6) of both extracts exhibited also a significant antifungal activity in a concentration-related manner (150–300 μg/well). The strains of Aspergillus fumigatus were more susceptible to these extracts and derived fractions, while those of Trichophyton rubrum were found to be less susceptible. No activity was observed against strains of Candida albicans . These findings suggest that the polar active fractions (F5, F6) obtained from aqueous and methanolic extracts could contain a new antifungal compound(s). The purification and the determination of chemical structure of compound(s) of these active fractions are under investigation.

Country
France
Related Organizations
Subjects by Vocabulary

Microsoft Academic Graph classification: biology Chemical structure Trichophyton rubrum biology.organism_classification Yeast Microbiology Aspergillus fumigatus Agar plate Mycology Food science Holothuria Candida albicans

Keywords

[SDV]Life Sciences [q-bio], [SDV] Life Sciences [q-bio], Infectious Diseases

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    41
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
41
Top 10%
Top 10%
Top 10%
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