Actions
  • shareshare
  • link
  • cite
  • add
add
auto_awesome_motion View all 7 versions
Publication . Article . 2016

What is memory? The present state of the engram.

Mu-ming Poo; Michele Pignatelli; Tomás J. Ryan; Susumu Tonegawa; Tobias Bonhoeffer; Kelsey C. Martin; Andrii Rudenko; +12 Authors
Open Access
Published: 19 May 2016
Publisher: eScholarship, University of California
Country: United States
Abstract
© 2016 Poo et al. The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous "excitations", whose precise physical nature and consequences were out of reach of the biology of his day. Neuroscientists now have the knowledge and tools to tackle this question, however, and this Forum brings together leading contemporary views on the mechanisms of memory and what the engram means today.
Subjects by Vocabulary

Microsoft Academic Graph classification: Biology Mechanism (sociology) Engram Pattern separation State (polity) media_common.quotation_subject media_common Cognitive science

Subjects

Spine, Brain, Hippocampus, Neurons, Synapses, Animals, Humans, Models, Animal, Memory, Epigenomics, Neurosciences, 1.1 Normal biological development and functioning, 1.2 Psychological and socioeconomic processes, Developmental Biology, Biological Sciences, Cell Biology, Developmental Biology, Plant Science, General Agricultural and Biological Sciences, General Biochemistry, Genetics and Molecular Biology, Physiology, Ecology, Evolution, Behavior and Systematics, Structural Biology, Biotechnology, Forum, Biochemistry, Genetics and Molecular Biology(all), Agricultural and Biological Sciences(all)

Related Organizations
Funded by
NIH| Localized mRNAs in Synaptic Plasticity
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R01NS045324-12
  • Funding stream: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Related to Research communities
Neuroinformatics
moresidebar